Endocrine Abstracts

The pathophysiology of aldosterone-producing adenomas (APA), especially those manifesting clinically overt hyperaldosteronism despite their small size, remains unknown. Therefore, we examined the correlation between tumor size and the status of intratumoral steroidogenic enzymes involved in aldosterone biosynthesis using immunohistochemistry. Forty patients with surgically proven APAs following adrenal venous sampling were retrospectively studied. The tumor area at the maximum...